CMap Candidate Details

Structure:
CMap ID: C01617
Pert ID: BRD-A67479912
Compound Name: progesterone
Targets: CYP17A1; NR3C2; PGR
MoA: Progesterone receptor agonist
SMILES: CC(=O)[C@H]1CCC2C3CCC4=CC(=O)CC[C@]4(C)C3CC[C@]12C
InchiKey: RJKFOVLPORLFTN-OYEBDCLDSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6679 BRD-A67479912 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7582 BRD-A67479912 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8773 BRD-A67479912 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
124985 BRD-A67479912 A549 0.37 uM 24 h 0.29 1.19 0.42 0.0 0.0 0.0
125012 BRD-A67479912 HA1E 0.125 uM 24 h 0.19 0.81 0.0 0.0 0.0 0.0
125088 BRD-A67479912 MCF10A 0.37 uM 24 h 0.27 1.15 0.32 0.0 0.0 0.0
125125 BRD-A67479912 MDAMB231 0.04 uM 24 h -0.2 -0.82 0.0 0.0 0.0 0.0
125188 BRD-A67479912 THP1 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125224 BRD-A67479912 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133078 BRD-A67479912 HEK293 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133104 BRD-A67479912 HELA 2.22 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.45
133134 BRD-A67479912 HT29 0.01 uM 24 h 0.0 0.0 0.0 0.31 1.11 0.71
133184 BRD-A67479912 JURKAT 0.08 uM 24 h 0.29 1.19 0.42 0.32 1.14 0.87
133246 BRD-A67479912 MCF??7.00 0.74 uM 24 h 0.26 1.07 0.19 0.0 0.0 0.0
133305 BRD-A67479912 PC3 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).