CMap Candidate Details

Structure:
CMap ID: C16173
Pert ID: BRD-K43330982
Compound Name: JTE-013
Targets: S1PR2
MoA: Lysophospholipid receptor antagonist
SMILES: CC(C)c1cc(NNC(=O)Nc2cc(Cl)nc(Cl)c2)nc2n(C)nc(C)c12
InchiKey: RNSLRQNDXRSASX-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3026 BRD-K43330982 HA1E 10 uM 6 h 0.0 0.0 0.0 0.21 0.73 0.03
3204 BRD-K43330982 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3625 BRD-K43330982 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3802 BRD-K43330982 VCAP 10 uM 24 h 0.2 0.83 0.0 -0.29 -0.98 0.47
41771 BRD-K43330982 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41936 BRD-K43330982 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42365 BRD-K43330982 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42689 BRD-K43330982 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42992 BRD-K43330982 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43191 BRD-K43330982 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43554 BRD-K43330982 NPC 10 uM 24 h -0.26 -1.09 0.32 -0.29 -0.97 0.46
43853 BRD-K43330982 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44119 BRD-K43330982 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99538 BRD-K43330982 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).