CMap Candidate Details

Structure:
CMap ID: C16199
Pert ID: BRD-K43405658
Compound Name: BRD-K43405658
Targets: --
MoA: --
SMILES: C[C@@H](NC(=O)/C(=C/c1ccc(O)c(O)c1)/C#N)c2ccccc2
InchiKey: UMGQVUWXNOJOSJ-KMHUVPDISA-N
Compound Aliases: tyrphostin-AG-527

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6753 BRD-K43405658 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6997 BRD-K43405658 A549 10 uM 24 h 0.0 0.0 0.0 0.25 0.87 0.17
7446 BRD-K43405658 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7658 BRD-K43405658 HCC515 10 uM 6 h -0.28 -1.15 0.45 -0.33 -1.11 0.91
7999 BRD-K43405658 HT29 10 uM 6 h -0.22 -0.93 0.07 0.0 0.0 0.0
8175 BRD-K43405658 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8371 BRD-K43405658 PC3 10 uM 24 h -0.26 -1.1 0.34 0.0 0.0 0.0
8817 BRD-K43405658 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
53451 BRD-K43405658 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
53511 BRD-K43405658 HUH7 2.5 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
53664 BRD-K43405658 PHH 10 uM 24 h 0.27 1.11 0.25 -0.31 -1.05 0.71
99540 BRD-K43405658 U2OS 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.96 0.43
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).