CMap Candidate Details

Structure:
CMap ID: C16202
Pert ID: BRD-K43410529
Compound Name: MLN-2480
Targets: --
MoA: --
SMILES: C[C@@H](NC(=O)c1ncnc(N)c1Cl)c1ncc(s1)C(=O)Nc1cc(c(Cl)cn1)C(F)(F)F
InchiKey: VWMJHAFYPMOMGF-ZCFIWIBFSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
123267 BRD-K43410529 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123281 BRD-K43410529 HA1E 10 uM 24 h -0.25 -1.04 0.21 0.0 0.0 0.0
123295 BRD-K43410529 HEK293 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.29
123323 BRD-K43410529 HELA 3.33 uM 24 h -0.19 -0.81 0.0 -0.41 -1.4 2.02
123355 BRD-K43410529 HT29 3.33 uM 24 h 0.24 0.99 0.09 0.23 0.8 0.08
123376 BRD-K43410529 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123437 BRD-K43410529 PC3 0.125 uM 24 h -0.29 -1.2 0.57 0.31 1.08 0.66
123472 BRD-K43410529 THP1 0.125 uM 24 h -0.22 -0.94 0.08 0.24 0.84 0.13
131534 BRD-K43410529 A375 2.22 uM 24 h 0.0 0.0 0.0 -0.23 -0.77 0.08
131744 BRD-K43410529 HUVEC 0.08 uM 24 h 0.0 0.0 0.0 -0.26 -0.86 0.22
131799 BRD-K43410529 JURKAT 0.25 uM 24 h -0.2 -0.82 0.0 0.0 0.0 0.0
131872 BRD-K43410529 MCF??7.00 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131904 BRD-K43410529 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.51
131961 BRD-K43410529 YAPC 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).