CMap Candidate Details

Structure:
CMap ID: C16227
Pert ID: BRD-K43471985
Compound Name: OTX-015
Targets: --
MoA: --
SMILES: Cc1sc-2c(c1C)C(=N[C@@H](CC(=O)Nc1ccc(O)cc1)c1nnc(C)n-21)c1ccc(Cl)cc1
InchiKey: GNMUEVRJHCWKTO-FQEVSTJZSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
90313 BRD-K43471985 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.19 -0.64 0.01
90597 BRD-K43471985 HCT116 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90669 BRD-K43471985 MCF10A 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96692 BRD-K43471985 PC3 10 uM 24 h 0.27 1.13 0.29 -0.41 -1.4 2.02
97306 BRD-K43471985 HAP1 0.66 uM 24 h 0.22 0.92 0.04 0.21 0.74 0.03
97991 BRD-K43471985 HA1E 10 uM 24 h 0.19 0.81 0.0 -0.37 -1.26 1.37
98021 BRD-K43471985 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.34
98067 BRD-K43471985 P1A82 0.37 uM 24 h 0.23 0.94 0.06 0.0 0.0 0.0
118693 BRD-K43471985 A375 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.24
118727 BRD-K43471985 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118803 BRD-K43471985 HCC515 0.37 uM 24 h 0.24 1.02 0.12 0.26 0.93 0.27
118845 BRD-K43471985 HEPG2 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.82
118888 BRD-K43471985 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).