CMap Candidate Details
Structure:
| CMap ID: | C01626 |
| Pert ID: | BRD-A67605442 |
| Compound Name: | tetrahydrobiopterin |
| Targets: | PAH; TH |
| MoA: | Nitric oxide stimulant; Nitric oxide synthase stimulant; Phenylalanine 4-hydroxylase stimulant |
| SMILES: | CC(O)[C@H](O)C1CNc2nc(N)[nH]c(=O)c2N1 |
| InchiKey: | FNKQXYHWGSIFBK-DGZDMUDUSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 49775 | BRD-A67605442 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50118 | BRD-A67605442 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50307 | BRD-A67605442 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.23 | -0.77 | 0.08 |
| 50469 | BRD-A67605442 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50637 | BRD-A67605442 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50810 | BRD-A67605442 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.41 | -1.38 | 2.02 |
| 50988 | BRD-A67605442 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 96088 | BRD-A67605442 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |