CMap Candidate Details

Structure:
CMap ID: C16265
Pert ID: BRD-K43586850
Compound Name: lacidipine
Targets: CACNA1C
MoA: Calcium channel blocker
SMILES: CCOC(=O)C1=C(C)NC(C)=C(C1c1ccccc1C=CC(=O)OC(C)(C)C)C(=O)OCC
InchiKey: GKQPCPXONLDCMU-CCEZHUSRSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91102 BRD-K43586850 HUH7 6.66 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
95527 BRD-K43586850 A549 10 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
95595 BRD-K43586850 MCF??7.00 10 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
95720 BRD-K43586850 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
121581 BRD-K43586850 HA1E 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121627 BRD-K43586850 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121652 BRD-K43586850 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121695 BRD-K43586850 YAPC 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129576 BRD-K43586850 A375 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129674 BRD-K43586850 PC3 0.01 uM 24 h 0.0 0.0 0.0 0.31 1.09 0.67
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).