CMap Candidate Details

Structure:
CMap ID: C16316
Pert ID: BRD-K43723251
Compound Name: chenodiol
Targets: HSD11B1
MoA: 11-beta-HSD1 inhibitor
SMILES: C[C@H](CCC(O)=O)[C@@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@@H]3CC[C@]12C
InchiKey: RUDATBOHQWOJDD-CIKBIKKZSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121582 BRD-K43723251 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.18
129577 BRD-K43723251 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129593 BRD-K43723251 HELA 0.74 uM 24 h 0.24 1.01 0.11 0.0 0.0 0.0
129623 BRD-K43723251 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129652 BRD-K43723251 MCF??7.00 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129675 BRD-K43723251 PC3 2.22 uM 24 h 0.26 1.08 0.21 0.27 0.96 0.33
129715 BRD-K43723251 YAPC 2.22 uM 24 h 0.27 1.14 0.32 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).