CMap Candidate Details

Structure:
CMap ID: C01632
Pert ID: BRD-A67788537
Compound Name: salermide
Targets: SIRT2; SIRT1
MoA: SIRT inhibitor
SMILES: CC(C(=O)Nc1cccc(c1)N=Cc1c(O)ccc2ccccc12)c1ccccc1
InchiKey: HQSSEGBEYORUBY-WPWMEQJKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9076 BRD-A67788537 A549 125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9301 BRD-A67788537 AGS 125 uM 6 h 0.26 1.07 0.2 0.0 0.0 0.0
9607 BRD-A67788537 H1299 125 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10012 BRD-A67788537 HA1E 125 uM 6 h 0.17 0.73 0.0 0.0 0.0 0.0
10242 BRD-A67788537 HCC515 125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10412 BRD-A67788537 HCT116 125 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10681 BRD-A67788537 HEPG2 125 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11121 BRD-A67788537 HT29 125 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11253 BRD-A67788537 MCF??7.00 125 uM 6 h 0.0 0.0 0.0 -0.49 -1.64 15.65
11355 BRD-A67788537 NCIH2073 125 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11927 BRD-A67788537 NCIH596 125 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12217 BRD-A67788537 NOMO1 125 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12572 BRD-A67788537 PC3 125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
12679 BRD-A67788537 SW480 125 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13545 BRD-A67788537 VCAP 125 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
95897 BRD-A67788537 YAPC 10 uM 6 h -0.21 -0.87 0.02 0.0 0.0 0.0
97038 BRD-A67788537 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98846 BRD-A67788537 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99203 BRD-A67788537 NPC 10 uM 6 h 0.0 0.0 0.0 0.31 1.09 0.67
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).