CMap Candidate Details

Structure:
CMap ID: C16323
Pert ID: BRD-K43764301
Compound Name: dexketoprofen
Targets: PTGS1; PTGS2
MoA: Cyclooxygenase inhibitor
SMILES: C[C@H](C(=O)O)c1cccc(c1)C(=O)c2ccccc2
InchiKey: DKYWVDODHFEZIM-NSHDSACASA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33676 BRD-K43764301 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34108 BRD-K43764301 ASC 10 uM 24 h -0.25 -1.06 0.26 0.3 1.08 0.64
34367 BRD-K43764301 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34625 BRD-K43764301 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.2 -0.67 0.02
34891 BRD-K43764301 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35150 BRD-K43764301 HT29 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.03 0.63
35451 BRD-K43764301 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.99 0.51
35787 BRD-K43764301 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36085 BRD-K43764301 PC3 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.0 0.52
36269 BRD-K43764301 PHH 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.88
36567 BRD-K43764301 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36970 BRD-K43764301 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91441 BRD-K43764301 HUH7 12.5 uM 72 h 0.27 1.12 0.27 0.0 0.0 0.0
96145 BRD-K43764301 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).