CMap Candidate Details

Structure:
CMap ID: C01633
Pert ID: BRD-A67799922
Compound Name: phenoxybenzamine
Targets: ADRA2B
MoA: Adrenergic receptor antagonist
SMILES: CC(COc1ccccc1)N(CCCl)Cc1ccccc1
InchiKey: QZVCTJOXCFMACW-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4024 BRD-A67799922 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4759 BRD-A67799922 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5005 BRD-A67799922 VCAP 10 uM 6 h 0.28 1.16 0.34 -0.27 -0.91 0.3
37095 BRD-A67799922 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37247 BRD-A67799922 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37534 BRD-A67799922 ASC 10 uM 24 h -0.25 -1.03 0.19 0.0 0.0 0.0
37842 BRD-A67799922 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38031 BRD-A67799922 HT29 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.82 0.15
38263 BRD-A67799922 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38381 BRD-A67799922 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
50308 BRD-A67799922 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.39 -1.3 1.67
91071 BRD-A67799922 HUH7 10 uM 72 h 0.21 0.88 0.01 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).