CMap Candidate Details

Structure:
CMap ID: C16342
Pert ID: BRD-K43802723
Compound Name: AMG-837
Targets: --
MoA: --
SMILES: CC#C[C@@H](CC(O)=O)c1ccc(OCc2cccc(c2)-c2ccc(cc2)C(F)(F)F)cc1
InchiKey: ZOPNBMMVVZRSGH-NRFANRHFSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121548 BRD-K43802723 A375 10 uM 24 h -0.24 -0.99 0.14 0.0 0.0 0.0
121583 BRD-K43802723 HA1E 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121628 BRD-K43802723 HELA 0.125 uM 24 h -0.24 -1.01 0.16 0.0 0.0 0.0
121653 BRD-K43802723 HT29 1.11 uM 24 h 0.22 0.93 0.05 0.0 0.0 0.0
121670 BRD-K43802723 MCF??7.00 0.125 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.05
121696 BRD-K43802723 YAPC 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129676 BRD-K43802723 PC3 0.03 uM 24 h 0.25 1.06 0.18 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).