CMap Candidate Details

Structure:
CMap ID: C16344
Pert ID: BRD-K43806473
Compound Name: camostat-mesilate
Targets: PRSS1
MoA: Trypsin inhibitor; Protease inhibitor; Peptidase inhibitor
SMILES: CN(C)C(=O)COC(=O)Cc1ccc(OC(=O)c2ccc(NC(N)=N)cc2)cc1
InchiKey: XASIMHXSUQUHLV-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121556 BRD-K43806473 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121595 BRD-K43806473 HA1E 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121657 BRD-K43806473 HT29 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.98 0.47
121676 BRD-K43806473 MCF??7.00 10 uM 24 h 0.23 0.94 0.06 0.0 0.0 0.0
129601 BRD-K43806473 HELA 0.08 uM 24 h 0.0 0.0 0.0 0.41 1.46 2.23
129686 BRD-K43806473 PC3 0.01 uM 24 h 0.23 0.97 0.08 0.32 1.12 0.77
129724 BRD-K43806473 YAPC 2.22 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.38
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).