CMap Candidate Details

Structure:
CMap ID: C16395
Pert ID: BRD-K43978949
Compound Name: PIT
Targets: P2RY1
MoA: Purinergic receptor antagonist
SMILES: [O-][N+]1=C(C(=O)c2ccccc12)c1ccccn1
InchiKey: LXEZPPZLNVOLDI-UHFFFAOYSA-N
Compound Aliases: pit

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2884 BRD-K43978949 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3369 BRD-K43978949 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3506 BRD-K43978949 PC3 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.86 0.2
3962 BRD-K43978949 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44399 BRD-K43978949 A375 10 uM 6 h -0.24 -0.98 0.12 0.0 0.0 0.0
44707 BRD-K43978949 A549 10 uM 6 h 0.0 0.0 0.0 0.28 0.99 0.4
45259 BRD-K43978949 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45528 BRD-K43978949 HT29 10 uM 6 h -0.23 -0.96 0.1 0.0 0.0 0.0
45697 BRD-K43978949 MCF??7.00 10 uM 24 h -0.2 -0.82 0.0 -0.25 -0.83 0.17
46080 BRD-K43978949 NPC 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.24
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).