CMap Candidate Details

Structure:
CMap ID: C16423
Pert ID: BRD-K44067360
Compound Name: flufenamic-acid
Targets: AR; PTGS1; PTGS2; AKR1C3
MoA: Chloride channel antagonist
SMILES: OC(=O)c1ccccc1Nc1cccc(c1)C(F)(F)F
InchiKey: LPEPZBJOKDYZAD-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3027 BRD-K44067360 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3507 BRD-K44067360 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3803 BRD-K44067360 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44400 BRD-K44067360 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44588 BRD-K44067360 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44965 BRD-K44067360 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45260 BRD-K44067360 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45529 BRD-K44067360 HT29 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.92 0.32
46397 BRD-K44067360 PHH 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.5
46718 BRD-K44067360 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51220 BRD-K44067360 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90977 BRD-K44067360 HUH7 12 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).