CMap Candidate Details
Structure:
| CMap ID: | C16489 |
| Pert ID: | BRD-K44276885 |
| Compound Name: | acarbose |
| Targets: | GAA; AMY2A; MGAM |
| MoA: | Glucosidase inhibitor |
| SMILES: | C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)O[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O |
| InchiKey: | XUFXOAAUWZOOIT-SXARVLRPSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 44589 | BRD-K44276885 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.28 | -0.95 | 0.39 |
| 44966 | BRD-K44276885 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 45261 | BRD-K44276885 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 46081 | BRD-K44276885 | NPC | 10 uM | 24 h | -0.29 | -1.21 | 0.58 | -0.29 | -0.97 | 0.45 |
| 46398 | BRD-K44276885 | PHH | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.29 | -0.99 | 0.5 |
| 46719 | BRD-K44276885 | SKB | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 49841 | BRD-K44276885 | A375 | 10 uM | 6 h | -0.29 | -1.23 | 0.63 | -0.26 | -0.88 | 0.26 |
| 50186 | BRD-K44276885 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50534 | BRD-K44276885 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50668 | BRD-K44276885 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50840 | BRD-K44276885 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.35 | 1.23 | 1.19 |
| 51149 | BRD-K44276885 | VCAP | 10 uM | 6 h | 0.24 | 1.0 | 0.11 | -0.32 | -1.08 | 0.78 |