CMap Candidate Details

Structure:
CMap ID: C01649
Pert ID: BRD-A68304895
Compound Name: BTS-54505
Targets: SLC6A2; SLC6A3; SLC6A4
MoA: Dopamine reuptake inhibitor; Serotonin reuptake inhibitor; Norepinephrine reputake inhibitor; Adrenergic transmitter uptake inhibitor
SMILES: CC(C)CC(N)C1(CCC1)c1ccc(Cl)cc1
InchiKey: WQSACWZKKZPCHN-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
126734 BRD-A68304895 HT29 10 uM 24 h 0.0 0.0 0.0 0.32 1.15 0.88
126827 BRD-A68304895 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126869 BRD-A68304895 MDAMB231 10 uM 24 h 0.24 1.01 0.12 0.27 0.96 0.33
126930 BRD-A68304895 THP1 0.37 uM 24 h 0.0 0.0 0.0 0.32 1.12 0.77
134669 BRD-A68304895 A375 2.22 uM 24 h 0.0 0.0 0.0 0.31 1.1 0.71
134692 BRD-A68304895 A549 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134718 BRD-A68304895 HA1E 0.01 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.19
134752 BRD-A68304895 HEK293 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134787 BRD-A68304895 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.29 1.03 0.5
134845 BRD-A68304895 HUVEC 0.01 uM 24 h 0.22 0.92 0.04 0.0 0.0 0.0
134896 BRD-A68304895 JURKAT 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134917 BRD-A68304895 MCF10A 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134954 BRD-A68304895 PC3 0.08 uM 24 h 0.24 0.99 0.1 0.28 0.98 0.39
134984 BRD-A68304895 YAPC 0.03 uM 24 h 0.0 0.0 0.0 -0.34 -1.13 0.98
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).