CMap Candidate Details

Structure:
CMap ID: C16499
Pert ID: BRD-K44309363
Compound Name: dexniguldipine
Targets: --
MoA: --
SMILES: COC(=O)C1=C(C)NC(C)=C([C@@H]1c1cccc(c1)[N+]([O-])=O)C(=O)OCCCN1CCC(CC1)(c1ccccc1)c1ccccc1
InchiKey: SVJMLYUFVDMUHP-MGBGTMOVSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
90607 BRD-K44309363 HCT116 3.33 uM 24 h -0.26 -1.07 0.28 0.0 0.0 0.0
90698 BRD-K44309363 MCF10A 0.37 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.26
98007 BRD-K44309363 HA1E 3.33 uM 24 h 0.23 0.95 0.06 0.31 1.11 0.72
98094 BRD-K44309363 P1A82 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99550 BRD-K44309363 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
123251 BRD-K44309363 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123297 BRD-K44309363 HEK293 0.04 uM 24 h 0.34 1.43 1.11 0.28 0.99 0.41
123357 BRD-K44309363 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123384 BRD-K44309363 MCF??7.00 10 uM 24 h 0.18 0.76 0.0 0.0 0.0 0.0
123406 BRD-K44309363 MDAMB231 0.125 uM 24 h 0.0 0.0 0.0 0.23 0.81 0.09
123440 BRD-K44309363 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123474 BRD-K44309363 THP1 10 uM 24 h 0.0 0.0 0.0 0.24 0.87 0.17
123510 BRD-K44309363 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131566 BRD-K44309363 A549 0.25 uM 24 h 0.24 1.0 0.1 0.23 0.8 0.08
131671 BRD-K44309363 HELA 2.22 uM 24 h 0.23 0.95 0.06 0.0 0.0 0.0
131748 BRD-K44309363 HUVEC 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131803 BRD-K44309363 JURKAT 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).