CMap Candidate Details
Structure:
| CMap ID: | C16514 |
| Pert ID: | BRD-K44366189 |
| Compound Name: | anacetrapib |
| Targets: | CETP |
| MoA: | Cholesteryl ester transfer protein inhibitor |
| SMILES: | COc1cc(F)c(cc1-c1ccc(cc1CN1[C@H](C)[C@H](OC1=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(F)(F)F)C(C)C |
| InchiKey: | MZZLGJHLQGUVPN-WZQKQDCOSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 121550 | BRD-K44366189 | A375 | 3.33 uM | 24 h | -0.28 | -1.19 | 0.52 | -0.22 | -0.75 | 0.06 |
| 121586 | BRD-K44366189 | HA1E | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.23 | -0.77 | 0.08 |
| 129596 | BRD-K44366189 | HELA | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129625 | BRD-K44366189 | HT29 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129655 | BRD-K44366189 | MCF??7.00 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.89 | 0.27 |
| 129678 | BRD-K44366189 | PC3 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.36 | -1.21 | 1.24 |
| 129718 | BRD-K44366189 | YAPC | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |