CMap Candidate Details

Structure:
CMap ID: C16539
Pert ID: BRD-K44432556
Compound Name: VU-0418946-1
Targets: HIF1A
MoA: HIF modulator
SMILES: C(Nc1nc(nnc1-c1ccccc1)-c1ccccn1)c1ccc(cc1)-c1ccccc1
InchiKey: QNRODODTMXCRKU-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
17346 BRD-K44432556 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
18288 BRD-K44432556 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
18592 BRD-K44432556 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
26365 BRD-K44432556 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
27941 BRD-K44432556 NEU 10 uM 24 h -0.18 -0.76 0.0 -0.37 -1.25 1.35
28253 BRD-K44432556 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
28887 BRD-K44432556 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
29217 BRD-K44432556 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118384 BRD-K44432556 A375 1.11 uM 24 h -0.25 -1.03 0.2 -0.36 -1.21 1.24
118422 BRD-K44432556 A549 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118455 BRD-K44432556 HA1E 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118496 BRD-K44432556 HCC515 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118582 BRD-K44432556 HT29 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118619 BRD-K44432556 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).