CMap Candidate Details

Structure:
CMap ID: C01659
Pert ID: BRD-A68631409
Compound Name: evodiamine
Targets: TRPV1
MoA: TRPV agonist; ATPase inhibitor
SMILES: CN1C2N(CCc3c2[nH]c2ccccc32)C(=O)c2ccccc12
InchiKey: TXDUTHBFYKGSAH-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8883 BRD-A68631409 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9302 BRD-A68631409 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9608 BRD-A68631409 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9912 BRD-A68631409 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10290 BRD-A68631409 HCC515 10 uM 6 h 0.23 0.96 0.07 0.32 1.12 0.77
10413 BRD-A68631409 HCT116 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.77 0.08
10682 BRD-A68631409 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10914 BRD-A68631409 HT29 10 uM 24 h -0.24 -1.01 0.16 0.0 0.0 0.0
11165 BRD-A68631409 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11356 BRD-A68631409 NCIH2073 10 uM 6 h 0.26 1.09 0.22 0.22 0.78 0.07
11928 BRD-A68631409 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.32 1.14 0.86
12479 BRD-A68631409 PC3 10 uM 24 h 0.0 0.0 0.0 0.32 1.13 0.83
13427 BRD-A68631409 VCAP 10 uM 24 h 0.0 0.0 0.0 0.3 1.08 0.65
96090 BRD-A68631409 A549 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.98 0.47
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).