CMap Candidate Details

Structure:
CMap ID: C01663
Pert ID: BRD-A68739437
Compound Name: NPK76-II-72-1
Targets: --
MoA: --
SMILES: COc1cc(ccc1Nc1ncc2N(C)C(=O)CC(C)N(C3CCCC3)c2n1)C(=O)NC1CCN(C)CC1
InchiKey: KZLQLABUFJNPSZ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33590 BRD-A68739437 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35060 BRD-A68739437 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
36161 BRD-A68739437 PHH 10 uM 24 h 0.31 1.28 0.61 0.0 0.0 0.0
36456 BRD-A68739437 SKB 10 uM 24 h 0.31 1.3 0.72 -0.39 -1.3 1.57
36743 BRD-A68739437 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91499 BRD-A68739437 BT20 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91567 BRD-A68739437 HS578T 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91631 BRD-A68739437 MCF10A 10 uM 6 h 0.0 0.0 0.0 0.31 1.09 0.67
91679 BRD-A68739437 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.29 1.04 0.56
91763 BRD-A68739437 SKBR3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
93605 BRD-A68739437 A549 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93678 BRD-A68739437 ASC 10 uM 24 h 0.18 0.77 0.0 0.0 0.0 0.0
93690 BRD-A68739437 CD34 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93744 BRD-A68739437 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.39
93778 BRD-A68739437 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93817 BRD-A68739437 HEK293 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93869 BRD-A68739437 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93908 BRD-A68739437 HEPG2 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93976 BRD-A68739437 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94004 BRD-A68739437 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94051 BRD-A68739437 MCF??7.00 10 uM 24 h -0.2 -0.84 0.01 -0.21 -0.71 0.03
94082 BRD-A68739437 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94168 BRD-A68739437 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94184 BRD-A68739437 PC3 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.55
94213 BRD-A68739437 SHSY5Y 1.11 uM 24 h 0.19 0.8 0.0 0.0 0.0 0.0
94266 BRD-A68739437 SKL 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94317 BRD-A68739437 THP1 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.71
94362 BRD-A68739437 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).