CMap Candidate Details

Structure:
CMap ID: C16683
Pert ID: BRD-K44876623
Compound Name: zolpidem
Targets: GABRA1; GABRA2; GABRA3
MoA: Benzodiazepine receptor agonist
SMILES: CN(C)C(=O)Cc1c(nc2ccc(C)cn12)-c1ccc(C)cc1
InchiKey: ZAFYATHCZYHLPB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1262 BRD-K44876623 A549 10 uM 6 h 0.28 1.15 0.33 -0.34 -1.14 1.01
1279 BRD-K44876623 MCF??7.00 0.12 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
1342 BRD-K44876623 U2OS 10 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
25372 BRD-K44876623 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
50364 BRD-K44876623 HCC515 10 uM 6 h 0.0 0.0 0.0 0.2 0.69 0.01
97128 BRD-K44876623 A375 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.41
125289 BRD-K44876623 HEK293 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125364 BRD-K44876623 HT29 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125386 BRD-K44876623 JURKAT 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.17
125468 BRD-K44876623 MDAMB231 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.23
125480 BRD-K44876623 PC3 0.04 uM 24 h -0.24 -0.98 0.13 0.0 0.0 0.0
125509 BRD-K44876623 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125537 BRD-K44876623 YAPC 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133378 BRD-K44876623 HA1E 0.03 uM 24 h 0.0 0.0 0.0 -0.31 -1.06 0.72
133407 BRD-K44876623 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133500 BRD-K44876623 MCF10A 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).