CMap Candidate Details

Structure:
CMap ID: C01671
Pert ID: BRD-A68891053
Compound Name: BW-B70C
Targets: ALOX5
MoA: Lipoxygenase inhibitor
SMILES: CC(C=Cc1cccc(Oc2ccc(F)cc2)c1)N(O)C(=O)N
InchiKey: UAIYNMRLUHHRMF-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1509 BRD-A68891053 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1840 BRD-A68891053 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2204 BRD-A68891053 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2692 BRD-A68891053 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41684 BRD-A68891053 A375 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.83 0.16
42027 BRD-A68891053 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42230 BRD-A68891053 ASC 10 uM 24 h -0.18 -0.73 0.0 0.28 0.98 0.36
42572 BRD-A68891053 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42876 BRD-A68891053 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43135 BRD-A68891053 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.23
43428 BRD-A68891053 NPC 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.16 1.11
43738 BRD-A68891053 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44024 BRD-A68891053 SKB 10 uM 24 h 0.0 0.0 0.0 0.29 1.01 0.45
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).