CMap Candidate Details

Structure:
CMap ID: C16760
Pert ID: BRD-K45068323
Compound Name: W-13
Targets: MYLK; PDE1A; CALM1
MoA: Calmodulin antagonist
SMILES: NCCCCNS(=O)(=O)c1ccc2c(Cl)cccc2c1
InchiKey: JJQKICOADUKSNS-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2885 BRD-K45068323 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3206 BRD-K45068323 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3963 BRD-K45068323 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42096 BRD-K45068323 A549 10 uM 6 h -0.26 -1.08 0.31 0.3 1.05 0.57
42367 BRD-K45068323 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42691 BRD-K45068323 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.3 1.06 0.6
42993 BRD-K45068323 HT29 10 uM 6 h 0.25 1.03 0.13 0.0 0.0 0.0
43321 BRD-K45068323 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43555 BRD-K45068323 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43855 BRD-K45068323 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96878 BRD-K45068323 A375 3.33 uM 24 h 0.0 0.0 0.0 -0.33 -1.13 0.97
96954 BRD-K45068323 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99555 BRD-K45068323 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).