CMap Candidate Details

Structure:
CMap ID: C16818
Pert ID: BRD-K45245728
Compound Name: ursodeoxycholyltaurine
Targets: --
MoA: --
SMILES: C[C@H](CCC(=O)NCCS(O)(=O)=O)[C@H]1CC[C@H]2[C@@H]3[C@@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
InchiKey: BHTRKEVKTKCXOH-LBSADWJPSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125232 BRD-K45245728 A375 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125271 BRD-K45245728 HA1E 0.37 uM 24 h 0.26 1.09 0.23 0.0 0.0 0.0
125295 BRD-K45245728 HEK293 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125347 BRD-K45245728 HELA 1.11 uM 24 h 0.0 0.0 0.0 0.26 0.91 0.24
125369 BRD-K45245728 HT29 10 uM 24 h 0.0 0.0 0.0 0.33 1.18 0.99
125390 BRD-K45245728 JURKAT 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125413 BRD-K45245728 MCF10A 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125431 BRD-K45245728 MCF??7.00 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125485 BRD-K45245728 PC3 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.89 0.27
133354 BRD-K45245728 A549 0.03 uM 24 h 0.0 0.0 0.0 -0.4 -1.35 2.02
133540 BRD-K45245728 MDAMB231 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133595 BRD-K45245728 THP1 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133619 BRD-K45245728 YAPC 2.22 uM 24 h -0.2 -0.85 0.01 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).