CMap Candidate Details

Structure:
CMap ID: C16829
Pert ID: BRD-K45275534
Compound Name: betrixaban
Targets: F10
MoA: Coagulation inhibitor
SMILES: COc1ccc(NC(=O)c2ccc(cc2)C(=N)N(C)C)c(c1)C(=O)Nc1ccc(Cl)cn1
InchiKey: XHOLNRLADUSQLD-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
127028 BRD-K45275534 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127049 BRD-K45275534 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127077 BRD-K45275534 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127111 BRD-K45275534 HELA 10 uM 24 h 0.0 0.0 0.0 0.28 1.0 0.42
127147 BRD-K45275534 HT29 3.33 uM 24 h 0.2 0.83 0.0 0.35 1.22 1.16
127188 BRD-K45275534 MCF10A 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.61
127217 BRD-K45275534 MCF??7.00 0.04 uM 24 h 0.26 1.06 0.19 0.0 0.0 0.0
127288 BRD-K45275534 THP1 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135055 BRD-K45275534 A549 0.74 uM 24 h -0.21 -0.87 0.02 0.39 1.38 2.17
135181 BRD-K45275534 JURKAT 0.03 uM 24 h -0.22 -0.9 0.04 -0.26 -0.89 0.26
135279 BRD-K45275534 MDAMB231 0.03 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.77
135300 BRD-K45275534 PC3 0.74 uM 24 h -0.23 -0.95 0.09 0.0 0.0 0.0
135331 BRD-K45275534 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).