CMap Candidate Details

Structure:
CMap ID: C16836
Pert ID: BRD-K45296539
Compound Name: ZD-7114
Targets: ADRB3
MoA: Adrenergic receptor agonist
SMILES: COCCNC(=O)COc1ccc(OCCNC[C@@H](O)COc2ccccc2)cc1
InchiKey: RVMBDLSFFNKKLG-GOSISDBHSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5207 BRD-K45296539 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5454 BRD-K45296539 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5776 BRD-K45296539 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5918 BRD-K45296539 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6190 BRD-K45296539 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6552 BRD-K45296539 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37291 BRD-K45296539 A549 10 uM 24 h -0.36 -1.48 1.43 -0.33 -1.12 0.96
37668 BRD-K45296539 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38088 BRD-K45296539 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38234 BRD-K45296539 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38493 BRD-K45296539 NPC 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.96 0.44
38731 BRD-K45296539 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38960 BRD-K45296539 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99558 BRD-K45296539 U2OS 10 uM 6 h 0.17 0.7 0.0 -0.27 -0.91 0.31
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).