CMap Candidate Details

Structure:
CMap ID: C16885
Pert ID: BRD-K45435259
Compound Name: SCH-23390
Targets: DRD1; DRD5; HTR2C
MoA: Dopamine receptor antagonist
SMILES: CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1
InchiKey: GOTMKOSCLKVOGG-OAHLLOKOSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3208 BRD-K45435259 HCC515 10 uM 24 h 0.0 0.0 0.0 0.26 0.92 0.25
3806 BRD-K45435259 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
19050 BRD-K45435259 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
19293 BRD-K45435259 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
19696 BRD-K45435259 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20357 BRD-K45435259 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20674 BRD-K45435259 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20910 BRD-K45435259 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
21470 BRD-K45435259 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40818 BRD-K45435259 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41122 BRD-K45435259 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41457 BRD-K45435259 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97462 BRD-K45435259 NKDBA 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).