CMap Candidate Details

Structure:
CMap ID: C16898
Pert ID: BRD-K45479396
Compound Name: BP-554
Targets: HTR1A
MoA: Serotonin receptor agonist
SMILES: C(COc1ccc2OCOc2c1)CN1CCN(CC1)c1ccccc1
InchiKey: VUSNBQDZGKZEDL-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2886 BRD-K45479396 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3209 BRD-K45479396 HCC515 10 uM 24 h 0.0 0.0 0.0 0.32 1.14 0.87
3626 BRD-K45479396 PC3 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.78 0.1
3807 BRD-K45479396 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39139 BRD-K45479396 A375 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.94 0.37
39453 BRD-K45479396 A549 10 uM 6 h 0.25 1.03 0.13 0.0 0.0 0.0
39702 BRD-K45479396 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40009 BRD-K45479396 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40280 BRD-K45479396 HT29 10 uM 6 h 0.0 0.0 0.0 0.27 0.95 0.31
40621 BRD-K45479396 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.38 1.35 1.72
40819 BRD-K45479396 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41123 BRD-K45479396 NPC 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.86 0.22
41458 BRD-K45479396 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99559 BRD-K45479396 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).