CMap Candidate Details

Structure:
CMap ID: C01691
Pert ID: BRD-A69512159
Compound Name: carbidopa
Targets: DDC
MoA: Aromatic L-amino acid decarboxylase inhibitor
SMILES: CC(Cc1ccc(O)c(O)c1)(NN)C(=O)O
InchiKey: TZFNLOMSOLWIDK-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
18907 BRD-A69512159 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
19218 BRD-A69512159 A549 10 uM 24 h 0.22 0.92 0.04 -0.31 -1.04 0.68
19558 BRD-A69512159 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
19879 BRD-A69512159 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20208 BRD-A69512159 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.3 1.08 0.65
20540 BRD-A69512159 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20839 BRD-A69512159 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
21483 BRD-A69512159 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
21500 BRD-A69512159 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90928 BRD-A69512159 HUH7 15 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
97687 BRD-A69512159 NKDBA 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98197 BRD-A69512159 NPC 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
98312 BRD-A69512159 NEU 10 uM 24 h -0.24 -0.99 0.14 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).