CMap Candidate Details

Structure:
CMap ID: C16913
Pert ID: BRD-K45503887
Compound Name: delivert
Targets: AGTR1; AGTR2
MoA: Angiotensin receptor agonist
SMILES: CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](N)CC(O)=O)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@@H]1C(=O)N[C@H](Cc1ccccc1)C(O)=O
InchiKey: CZGUSIXMZVURDU-FCWOTDAASA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125234 BRD-K45503887 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125299 BRD-K45503887 HEK293 3.33 uM 24 h 0.27 1.14 0.32 0.17 0.6 0.0
125434 BRD-K45503887 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125471 BRD-K45503887 MDAMB231 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125488 BRD-K45503887 PC3 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133358 BRD-K45503887 A549 0.01 uM 24 h 0.21 0.89 0.02 0.29 1.03 0.51
133382 BRD-K45503887 HA1E 0.74 uM 24 h 0.0 0.0 0.0 -0.39 -1.33 1.71
133410 BRD-K45503887 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133445 BRD-K45503887 HT29 0.01 uM 24 h -0.23 -0.96 0.1 -0.16 -0.53 0.0
133475 BRD-K45503887 JURKAT 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133506 BRD-K45503887 MCF10A 0.74 uM 24 h 0.21 0.89 0.02 0.0 0.0 0.0
133599 BRD-K45503887 THP1 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133621 BRD-K45503887 YAPC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).