CMap Candidate Details

Structure:
CMap ID: C17019
Pert ID: BRD-K45842176
Compound Name: BRD-K45842176
Targets: --
MoA: --
SMILES: COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73
InchiKey: HMSQNPMOULJFRY-VPNVGQJSSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25556 BRD-K45842176 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25940 BRD-K45842176 A549 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.79 0.1
26369 BRD-K45842176 ASC 10 uM 24 h 0.29 1.21 0.45 0.0 0.0 0.0
26700 BRD-K45842176 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
27003 BRD-K45842176 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
27313 BRD-K45842176 HT29 10 uM 6 h 0.0 0.0 0.0 0.36 1.28 1.37
27716 BRD-K45842176 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.0 0.52
28257 BRD-K45842176 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
28486 BRD-K45842176 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
29220 BRD-K45842176 SKB 10 uM 24 h 0.27 1.14 0.32 0.29 1.04 0.54
29490 BRD-K45842176 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).