CMap Candidate Details

Structure:
CMap ID: C01702
Pert ID: BRD-A69927616
Compound Name: isradipine
Targets: CACNA1C; CACNA1D; CACNA1F; CACNA1S; CACNA2D1
MoA: Calcium channel blocker
SMILES: COC(=O)C1C(C(=C(C)N=C1C)C(=O)OC(C)C)c2cccc3nonc23
InchiKey: QVGAECMHUSHDCG-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24394 BRD-A69927616 A375 10 uM 6 h 0.0 0.0 0.0 -0.37 -1.25 1.35
24645 BRD-A69927616 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24854 BRD-A69927616 HT29 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.21 1.24
24994 BRD-A69927616 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25223 BRD-A69927616 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25305 BRD-A69927616 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98120 BRD-A69927616 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98559 BRD-A69927616 NEU 10 uM 6 h 0.21 0.89 0.02 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).