CMap Candidate Details

Structure:
CMap ID: C17033
Pert ID: BRD-K45875383
Compound Name: XBD-173
Targets: --
MoA: --
SMILES: CCN(Cc1ccccc1)C(=O)Cn1c2nc(ncc2n(C)c1=O)-c1ccccc1
InchiKey: NBMBIEOUVBHEBM-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125586 BRD-K45875383 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125615 BRD-K45875383 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125697 BRD-K45875383 HT29 0.37 uM 24 h -0.18 -0.74 0.0 0.0 0.0 0.0
125738 BRD-K45875383 HUVEC 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125779 BRD-K45875383 JURKAT 0.37 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.41
125829 BRD-K45875383 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.21 -0.72 0.04
125895 BRD-K45875383 THP1 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125936 BRD-K45875383 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133702 BRD-K45875383 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133733 BRD-K45875383 HEK293 0.25 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.5
133770 BRD-K45875383 HELA 2.22 uM 24 h 0.0 0.0 0.0 -0.31 -1.06 0.73
133860 BRD-K45875383 MCF10A 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133915 BRD-K45875383 MDAMB231 2.22 uM 24 h -0.22 -0.91 0.05 0.0 0.0 0.0
133945 BRD-K45875383 PC3 2.22 uM 24 h 0.21 0.87 0.01 -0.22 -0.74 0.05
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).