CMap Candidate Details

Structure:
CMap ID: C01704
Pert ID: BRD-A69951442
Compound Name: dexamethasone
Targets: NR3C1
MoA: Glucocorticoid receptor agonist
SMILES: C[C@@H]1CC2C3CCC4=CC(=O)C=CC4(C)[C@]3(F)[C@@H](O)CC2(C)[C@]1(O)C(=O)CO
InchiKey: UREBDLICKHMUKA-HIERVMNKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9303 BRD-A69951442 AGS 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.07 0.75
10351 BRD-A69951442 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.07 0.76
10683 BRD-A69951442 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.92 0.32
11357 BRD-A69951442 NCIH2073 10 uM 6 h 0.0 0.0 0.0 -0.38 -1.29 1.53
11929 BRD-A69951442 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12218 BRD-A69951442 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12559 BRD-A69951442 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
12680 BRD-A69951442 SW480 10 uM 6 h 0.34 1.4 1.02 0.0 0.0 0.0
13160 BRD-A69951442 U937 10 uM 6 h -0.24 -1.02 0.18 0.0 0.0 0.0
13546 BRD-A69951442 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
124308 BRD-A69951442 HA1E 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124434 BRD-A69951442 JURKAT 10 uM 24 h 0.0 0.0 0.0 -0.4 -1.34 1.85
124456 BRD-A69951442 MCF10A 10 uM 24 h 0.22 0.93 0.05 0.0 0.0 0.0
132340 BRD-A69951442 A375 0.74 uM 24 h 0.0 0.0 0.0 0.36 1.28 1.41
132370 BRD-A69951442 A549 0.03 uM 24 h 0.23 0.96 0.07 0.0 0.0 0.0
132432 BRD-A69951442 HEK293 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132450 BRD-A69951442 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132471 BRD-A69951442 HT29 0.25 uM 24 h 0.24 1.01 0.12 0.0 0.0 0.0
132535 BRD-A69951442 MCF??7.00 0.74 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.46
132563 BRD-A69951442 MDAMB231 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132623 BRD-A69951442 THP1 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132649 BRD-A69951442 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).