CMap Candidate Details

Structure:
CMap ID: C17040
Pert ID: BRD-K45888792
Compound Name: huperzine-a
Targets: ACHE
MoA: Glutamate receptor antagonist; Acetylcholinesterase inhibitor
SMILES: CC=C1[C@@H]2Cc3nc(O)ccc3[C@@]1(N)CC(C)=C2
InchiKey: ZRJBHWIHUMBLCN-SEQYCRGISA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24441 BRD-K45888792 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24580 BRD-K45888792 A549 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.45
24777 BRD-K45888792 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.09 0.82
24909 BRD-K45888792 HT29 10 uM 6 h 0.18 0.75 0.0 -0.33 -1.1 0.88
25025 BRD-K45888792 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25162 BRD-K45888792 PC3 10 uM 24 h -0.23 -0.97 0.11 0.29 1.01 0.46
25513 BRD-K45888792 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).