CMap Candidate Details

Structure:
CMap ID: C01709
Pert ID: BRD-A70155556
Compound Name: lovastatin
Targets: HMGCR
MoA: HMGCR inhibitor
SMILES: CCC(C)C(=O)OC1CC(C)C=C2C=CC(C)C(CCC(O)CC(O)CC(=O)O)C12
InchiKey: QLJODMDSTUBWDW-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8884 BRD-A70155556 A375 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9077 BRD-A70155556 A549 40 uM 24 h -0.17 -0.72 0.0 0.24 0.85 0.15
9304 BRD-A70155556 AGS 40 uM 6 h 0.19 0.81 0.0 -0.29 -0.99 0.5
9609 BRD-A70155556 H1299 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10013 BRD-A70155556 HA1E 40 uM 6 h -0.22 -0.9 0.04 0.45 1.6 2.38
10140 BRD-A70155556 HCC515 40 uM 24 h 0.0 0.0 0.0 0.31 1.11 0.71
10414 BRD-A70155556 HCT116 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10684 BRD-A70155556 HEPG2 40 uM 6 h 0.0 0.0 0.0 0.29 1.03 0.51
10915 BRD-A70155556 HT29 40 uM 24 h 0.0 0.0 0.0 0.33 1.17 0.93
11152 BRD-A70155556 MCF??7.00 40 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.38
11358 BRD-A70155556 NCIH2073 40 uM 6 h 0.0 0.0 0.0 0.36 1.26 1.29
11665 BRD-A70155556 NCIH508 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11930 BRD-A70155556 NCIH596 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12219 BRD-A70155556 NOMO1 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12458 BRD-A70155556 PC3 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
12681 BRD-A70155556 SW480 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12966 BRD-A70155556 THP1 40 uM 6 h 0.0 0.0 0.0 0.25 0.9 0.21
13428 BRD-A70155556 VCAP 40 uM 24 h 0.0 0.0 0.0 0.38 1.33 1.72
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).