CMap Candidate Details

Structure:
CMap ID: C17125
Pert ID: BRD-K46137903
Compound Name: prednicarbate
Targets: NR3C1
MoA: Phospholipase activator
SMILES: CCOC(=O)O[C@@]1(CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C)C(=O)COC(=O)CC
InchiKey: FNPXMHRZILFCKX-YKGOFRARSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5334 BRD-K46137903 HA1E 10 uM 24 h 0.0 0.0 0.0 0.37 1.32 1.63
5779 BRD-K46137903 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.08 0.81
5920 BRD-K46137903 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6192 BRD-K46137903 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6555 BRD-K46137903 VCAP 10 uM 6 h 0.0 0.0 0.0 0.29 1.02 0.48
37164 BRD-K46137903 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37389 BRD-K46137903 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37671 BRD-K46137903 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38090 BRD-K46137903 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38235 BRD-K46137903 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38495 BRD-K46137903 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38963 BRD-K46137903 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).