CMap Candidate Details

Structure:
CMap ID: C17151
Pert ID: BRD-K46211610
Compound Name: tolazoline
Targets: ADRA2A; ADRA2B; ADRA2C
MoA: Adrenergic receptor antagonist
SMILES: C(C1=NCCN1)c1ccccc1
InchiKey: JIVZKJJQOZQXQB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
7325 BRD-K46211610 HA1E 10 uM 24 h 0.0 0.0 0.0 0.32 1.15 0.88
7869 BRD-K46211610 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8818 BRD-K46211610 VCAP 10 uM 6 h 0.0 0.0 0.0 0.29 1.03 0.51
49846 BRD-K46211610 A375 10 uM 6 h 0.21 0.87 0.01 0.0 0.0 0.0
50013 BRD-K46211610 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50930 BRD-K46211610 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
51337 BRD-K46211610 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
99565 BRD-K46211610 U2OS 10 uM 6 h -0.2 -0.84 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).