CMap Candidate Details

Structure:
CMap ID: C01716
Pert ID: BRD-A70449690
Compound Name: forskolin
Targets: ADCY2
MoA: Adenylyl cyclase activator
SMILES: CC(=O)OC1C(O)C2C(C)(C)CCC(O)C2(C)C2(O)C(=O)CC(C)(OC12C)C=C
InchiKey: OHCQJHSOBUTRHG-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9041 BRD-A70449690 A375 10 uM 6 h 0.22 0.93 0.05 0.0 0.0 0.0
9150 BRD-A70449690 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9305 BRD-A70449690 AGS 10 uM 6 h 0.25 1.04 0.15 0.26 0.93 0.28
9931 BRD-A70449690 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.42 -1.42 3.04
10309 BRD-A70449690 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10685 BRD-A70449690 HEPG2 10 uM 6 h 0.22 0.91 0.03 -0.31 -1.03 0.62
11088 BRD-A70449690 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11187 BRD-A70449690 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11359 BRD-A70449690 NCIH2073 10 uM 6 h 0.28 1.16 0.34 0.32 1.14 0.87
11666 BRD-A70449690 NCIH508 10 uM 6 h -0.25 -1.05 0.22 -0.33 -1.11 0.91
11931 BRD-A70449690 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.25 0.9 0.21
12504 BRD-A70449690 PC3 10 uM 24 h 0.0 0.0 0.0 -0.42 -1.41 2.02
12682 BRD-A70449690 SW480 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13025 BRD-A70449690 THP1 10 uM 6 h 0.0 0.0 0.0 0.21 0.74 0.04
13161 BRD-A70449690 U937 10 uM 6 h 0.24 1.01 0.12 -0.32 -1.09 0.82
13547 BRD-A70449690 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).