CMap Candidate Details

Structure:
CMap ID: C17214
Pert ID: BRD-K46424862
Compound Name: hymecromone
Targets: MAOA; MAOB
MoA: Monoamine oxidase inhibitor
SMILES: Cc1cc(=O)oc2cc(O)ccc12
InchiKey: HSHNITRMYYLLCV-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6998 BRD-K46424862 A549 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.87
7662 BRD-K46424862 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8509 BRD-K46424862 PC3 10 uM 6 h -0.25 -1.05 0.24 0.3 1.07 0.63
8819 BRD-K46424862 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
125303 BRD-K46424862 HEK293 0.04 uM 24 h 0.0 0.0 0.0 -0.17 -0.56 0.0
125394 BRD-K46424862 JURKAT 0.04 uM 24 h -0.16 -0.66 0.0 0.22 0.77 0.05
125438 BRD-K46424862 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 0.28 0.99 0.39
133334 BRD-K46424862 A375 0.01 uM 24 h 0.25 1.04 0.15 0.29 1.03 0.5
133384 BRD-K46424862 HA1E 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133413 BRD-K46424862 HELA 0.03 uM 24 h 0.23 0.97 0.08 -0.35 -1.17 1.12
133448 BRD-K46424862 HT29 0.03 uM 24 h 0.28 1.15 0.33 0.0 0.0 0.0
133509 BRD-K46424862 MCF10A 0.08 uM 24 h 0.21 0.86 0.01 0.0 0.0 0.0
133546 BRD-K46424862 MDAMB231 0.03 uM 24 h 0.0 0.0 0.0 -0.38 -1.3 1.57
133602 BRD-K46424862 THP1 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133624 BRD-K46424862 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).