CMap Candidate Details

Structure:
CMap ID: C17221
Pert ID: BRD-K46441700
Compound Name: GR-55562
Targets: HTR1B
MoA: Serotonin receptor antagonist
SMILES: CN(C)CCCc1cc(ccc1O)C(=O)Nc2ccc(cc2)c3ccncc3
InchiKey: ZAGAUUVCYGSPBP-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3031 BRD-K46441700 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3212 BRD-K46441700 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3511 BRD-K46441700 PC3 10 uM 24 h 0.24 0.99 0.09 -0.33 -1.11 0.9
3810 BRD-K46441700 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39141 BRD-K46441700 A375 10 uM 6 h 0.0 0.0 0.0 0.23 0.81 0.09
39455 BRD-K46441700 A549 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.11 0.9
39705 BRD-K46441700 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40011 BRD-K46441700 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40283 BRD-K46441700 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40476 BRD-K46441700 MCF??7.00 10 uM 24 h -0.23 -0.97 0.11 -0.24 -0.79 0.11
41126 BRD-K46441700 NPC 10 uM 24 h -0.21 -0.87 0.02 0.0 0.0 0.0
41461 BRD-K46441700 SKB 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.4
99568 BRD-K46441700 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).