CMap Candidate Details
Structure:
| CMap ID: | C17240 |
| Pert ID: | BRD-K46503544 |
| Compound Name: | etoposide |
| Targets: | TOP2A; TOP2B |
| MoA: | Topoisomerase inhibitor |
| SMILES: | COc1cc(cc(OC)c1O)[C@H]1[C@H]2[C@@H](COC2=O)[C@H](O[C@@H]2O[C@@H]3CO[C@@H](C)O[C@H]3[C@H](O)[C@H]2O)c2cc3OCOc3cc12 |
| InchiKey: | VJJPUSNTGOMMGY-GGDFOFTDSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 51223 | BRD-K46503544 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 51471 | BRD-K46503544 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.3 | -0.99 | 0.51 |
| 88557 | BRD-K46503544 | VCAP | 2.22 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |