CMap Candidate Details

Structure:
CMap ID: C17265
Pert ID: BRD-K46574442
Compound Name: BRD-K46574442
Targets: --
MoA: --
SMILES: CC(C)C#Cc1ccc(cc1)[C@@H]1[C@@H](CO)N([C@@H]1C#N)C(=O)c1cccc(F)c1
InchiKey: DGEMMPDKDCWCNC-VSKRKVRLSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
60264 BRD-K46574442 VCAP 4 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
85775 BRD-K46574442 A375 10 uM 24 h 0.0 0.0 0.0 0.38 1.34 1.72
85866 BRD-K46574442 A549 20 uM 24 h 0.0 0.0 0.0 -0.44 -1.47 15.35
85957 BRD-K46574442 HA1E 20 uM 24 h 0.23 0.95 0.06 0.32 1.15 0.88
86065 BRD-K46574442 HCC515 20 uM 24 h 0.23 0.95 0.06 -0.3 -1.0 0.55
86171 BRD-K46574442 HEPG2 20 uM 24 h 0.0 0.0 0.0 -0.39 -1.32 1.71
86273 BRD-K46574442 HT29 20 uM 24 h 0.2 0.84 0.0 0.45 1.58 2.36
86356 BRD-K46574442 MCF??7.00 20 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
86445 BRD-K46574442 PC3 20 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.14
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).