CMap Candidate Details

Structure:
CMap ID: C17294
Pert ID: BRD-K46652470
Compound Name: nizatidine
Targets: HRH2
MoA: Histamine receptor antagonist
SMILES: CNC(NCCSCc1csc(CN(C)C)n1)=C[N+]([O-])=O
InchiKey: SGXXNSQHWDMGGP-WDZFZDKYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4117 BRD-K46652470 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4438 BRD-K46652470 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4808 BRD-K46652470 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4934 BRD-K46652470 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44408 BRD-K46652470 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44712 BRD-K46652470 A549 10 uM 6 h -0.23 -0.97 0.11 0.0 0.0 0.0
44973 BRD-K46652470 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45268 BRD-K46652470 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45537 BRD-K46652470 HT29 10 uM 6 h -0.29 -1.2 0.57 0.0 0.0 0.0
45702 BRD-K46652470 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.18
46404 BRD-K46652470 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46727 BRD-K46652470 SKB 10 uM 24 h 0.33 1.36 0.96 -0.29 -0.97 0.46
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).