CMap Candidate Details

Structure:
CMap ID: C17296
Pert ID: BRD-K46654563
Compound Name: zofenopril-calcium
Targets: ACE
MoA: Angiotensin converting enzyme inhibitor
SMILES: C[C@H](CSC(=O)c1ccccc1)C(=O)N1C[C@H](C[C@H]1C(O)=O)Sc1ccccc1
InchiKey: IAIDUHCBNLFXEF-MNEFBYGVSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125255 BRD-K46654563 A549 3.33 uM 24 h -0.24 -0.99 0.13 0.0 0.0 0.0
125276 BRD-K46654563 HA1E 0.125 uM 24 h 0.0 0.0 0.0 -0.39 -1.32 1.71
125304 BRD-K46654563 HEK293 0.37 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.81
125439 BRD-K46654563 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.58
125513 BRD-K46654563 THP1 10 uM 24 h -0.19 -0.81 0.0 0.0 0.0 0.0
133335 BRD-K46654563 A375 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133414 BRD-K46654563 HELA 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133449 BRD-K46654563 HT29 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133478 BRD-K46654563 JURKAT 0.03 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.48
133510 BRD-K46654563 MCF10A 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133547 BRD-K46654563 MDAMB231 0.25 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.27
133578 BRD-K46654563 PC3 2.22 uM 24 h 0.24 1.0 0.1 0.0 0.0 0.0
133625 BRD-K46654563 YAPC 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).