CMap Candidate Details

Structure:
CMap ID: C00173
Pert ID: BRD-A06784547
Compound Name: MRS-1334
Targets: ADORA3
MoA: Adenosine receptor antagonist
SMILES: CCOC(=O)C1=C(C)NC(=C(C1C#Cc2ccccc2)C(=O)OCc3ccc(cc3)[N+](=O)[O-])c4ccccc4
InchiKey: QFLOJAMZLQXHFS-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5143 BRD-A06784547 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5248 BRD-A06784547 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5491 BRD-A06784547 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6120 BRD-A06784547 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6448 BRD-A06784547 VCAP 10 uM 6 h -0.19 -0.81 0.0 0.34 1.21 1.15
41864 BRD-A06784547 A549 10 uM 24 h 0.0 0.0 0.0 0.31 1.1 0.7
42167 BRD-A06784547 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42513 BRD-A06784547 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.29 1.03 0.5
42823 BRD-A06784547 HT29 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.07 0.76
43105 BRD-A06784547 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.33 1.71
43370 BRD-A06784547 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43686 BRD-A06784547 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43985 BRD-A06784547 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).