CMap Candidate Details

Structure:
CMap ID: C17305
Pert ID: BRD-K46678324
Compound Name: BRD-K46678324
Targets: --
MoA: --
SMILES: Clc1cc(Cl)c(NC(=O)Nc2ccncc2)c(Cl)c1
InchiKey: GBOKNHVRVRMECW-UHFFFAOYSA-N
Compound Aliases: RHO-kinase-inhibitor-II

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6881 BRD-K46678324 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6999 BRD-K46678324 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7447 BRD-K46678324 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7663 BRD-K46678324 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7870 BRD-K46678324 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8096 BRD-K46678324 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8510 BRD-K46678324 PC3 10 uM 6 h 0.28 1.17 0.37 0.0 0.0 0.0
8681 BRD-K46678324 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.67
99279 BRD-K46678324 U2OS 50 uM 6 h 0.23 0.95 0.06 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).