CMap Candidate Details
Structure:
| CMap ID: | C17308 |
| Pert ID: | BRD-K46692793 |
| Compound Name: | umeclidinium |
| Targets: | CHRM1; CHRM3 |
| MoA: | Acetylcholine receptor antagonist |
| SMILES: | OC(c1ccccc1)(c1ccccc1)C12CC[N+](CCOCc3ccccc3)(CC1)CC2 |
| InchiKey: | FVTWTVQXNAJTQP-UHFFFAOYSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 125256 | BRD-K46692793 | A549 | 1.11 uM | 24 h | 0.16 | 0.66 | 0.0 | -0.19 | -0.63 | 0.0 |
| 125277 | BRD-K46692793 | HA1E | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 125307 | BRD-K46692793 | HEK293 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 125372 | BRD-K46692793 | HT29 | 3.33 uM | 24 h | -0.23 | -0.98 | 0.12 | 0.0 | 0.0 | 0.0 |
| 125441 | BRD-K46692793 | MCF??7.00 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.25 | -0.84 | 0.17 |
| 125515 | BRD-K46692793 | THP1 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 125545 | BRD-K46692793 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.3 | -1.01 | 0.58 |
| 133337 | BRD-K46692793 | A375 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 133416 | BRD-K46692793 | HELA | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 133481 | BRD-K46692793 | JURKAT | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.26 | 0.92 | 0.26 |
| 133513 | BRD-K46692793 | MCF10A | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.34 | -1.13 | 0.98 |
| 133550 | BRD-K46692793 | MDAMB231 | 2.22 uM | 24 h | 0.26 | 1.07 | 0.19 | 0.0 | 0.0 | 0.0 |
| 133580 | BRD-K46692793 | PC3 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |